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LOXL2 Antikörper (AA 26-776)

LOXL2 Reaktivität: Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7177405
  • Target Alle LOXL2 Antikörper anzeigen
    LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))
    Bindungsspezifität
    • 11
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 26-776
    Reaktivität
    • 58
    • 28
    • 25
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 71
    • 6
    Kaninchen
    Klonalität
    • 62
    • 15
    Polyklonal
    Konjugat
    • 39
    • 11
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser LOXL2 Antikörper ist unkonjugiert
    Applikation
    • 51
    • 28
    • 22
    • 7
    • 7
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Mouse Lysyl oxidase homolog 2 protein (26-776AA)
    Isotyp
    IgG
    Top Product
    Discover our top product LOXL2 Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:1000-1:5000,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))
    Andere Bezeichnung
    Loxl2 (LOXL2 Produkte)
    Hintergrund

    Background: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and specifically mediates deamination of trimethylated Lys-4 of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. Involved in epithelial to mesenchymal transition (EMT) via interaction with SNAI1 and participates in repression of E-cadherin, probably by mediating deamination of histone H3 By similarity. Acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation.

    Aliases: Loxl2Lysyl oxidase homolog 2 antibody, EC 1.4.3.13 antibody, Lysyl oxidase-like protein 2 antibody

    UniProt
    P58022
    Pathways
    Chromatin Binding
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