LOXL2 Antikörper (AA 26-776)
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- Target Alle LOXL2 Antikörper anzeigen
- LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))
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Bindungsspezifität
- AA 26-776
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser LOXL2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Mouse Lysyl oxidase homolog 2 protein (26-776AA)
- Isotyp
- IgG
- Top Product
- Discover our top product LOXL2 Primärantikörper
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- Applikationshinweise
- Recommended dilution: WB:1:1000-1:5000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))
- Andere Bezeichnung
- Loxl2 (LOXL2 Produkte)
- Synonyme
- LOR2 antikoerper, WS9-14 antikoerper, CG4402 antikoerper, Dmel\\CG4402 antikoerper, Dmloxl-2 antikoerper, dmlox-2 antikoerper, 1110004B06Rik antikoerper, 4930526G11Rik antikoerper, 9430067E15Rik antikoerper, GB13360 antikoerper, lox2-like antikoerper, LOXL2 antikoerper, lor2 antikoerper, loxl-2 antikoerper, ws9-14 antikoerper, im:7136137 antikoerper, si:dkeyp-32b1.1 antikoerper, wu:fk12g04 antikoerper, zgc:158414 antikoerper, lysyl oxidase like 2 antikoerper, lysyl oxidase-like 2 antikoerper, lysyl oxidase homolog 4 antikoerper, lysyl oxidase like 2 L homeolog antikoerper, lysyl oxidase-like 2b antikoerper, LOXL2 antikoerper, lox2 antikoerper, Loxl2 antikoerper, LOC408544 antikoerper, loxl2.L antikoerper, loxl2 antikoerper, loxl2b antikoerper
- Hintergrund
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Background: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and specifically mediates deamination of trimethylated Lys-4 of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. Involved in epithelial to mesenchymal transition (EMT) via interaction with SNAI1 and participates in repression of E-cadherin, probably by mediating deamination of histone H3 By similarity. Acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation.
Aliases: Loxl2Lysyl oxidase homolog 2 antibody, EC 1.4.3.13 antibody, Lysyl oxidase-like protein 2 antibody
- UniProt
- P58022
- Pathways
- Chromatin Binding
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