TUSC2 Antikörper (AA 31-100)

Produktnummer ABIN713546

Produktdetails anti-TUSC2 Antikörper

Target: TUSC2 (Tumor Suppressor Candidate 2 (TUSC2))

Bindungsspezifität: AA 31-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TUSC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TUSC2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu TUSC2

Target: TUSC2 (Tumor Suppressor Candidate 2 (TUSC2))

Andere Bezeichnung: TUSC2 (TUSC2 Produkte)

Synonyme: C3orf11 antikoerper, FUS1 antikoerper, PAP antikoerper, PDAP2 antikoerper, TUSC2 antikoerper, 1190001E22Rik antikoerper, AA407686 antikoerper, Fus1 antikoerper, Lgcc antikoerper, Pdap2 antikoerper, zgc:92701 antikoerper, zgc:153746 antikoerper, tumor suppressor candidate 2 antikoerper, tumor suppressor candidate 2 L homeolog antikoerper, tumor suppressor candidate 2b antikoerper, tumor suppressor candidate 2a antikoerper, TUSC2 antikoerper, tusc2.L antikoerper, Tusc2 antikoerper, tusc2b antikoerper, tusc2a antikoerper

Hintergrund:

Synonyms: C3orf11, FUS1, Fusion 1 protein, PAP, PDAP2, PDGFA associated protein 2, Tumor suppressor candidate 2, TUSC 2, TUSC2_HUMAN.

Background: TUSC2/FUS1 is a novel tumor suppressor gene identified in the human chromosome 3p21.3 region where allele losses and genetic alterations occur early and frequently for many human cancers. Expression of TUSC2 protein is absent or reduced in the majority of lung cancers and premalignant lung lesions. Restoration of TUSC2 function in 3p21.3-deficient non-small cell lung carcinoma cells significantly inhibits tumor cell growth by induction of apoptosis and alteration of cell cycle kinetics. TUSC2 may induce apoptosis through the activation of the intrinsic mitochondrial-dependent and Apaf-1-associated pathways and inhibit the function of protein tyrosine kinases including EGFR, PDGFR, AKT, c-Abl, and c-Kit.

Gen-ID: 11334