Perforin 1 Antikörper (AA 21-554)

Produktnummer ABIN7177734

Produktdetails anti-Perforin 1 Antikörper

Target: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Bindungsspezifität: AA 21-554

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Perforin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Mouse Perforin-1 protein (21-554AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Perforin 1

Target: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Andere Bezeichnung: Prf1 (PRF1 Produkte)

Synonyme: FLH2 antikoerper, HPLH2 antikoerper, P1 antikoerper, PFN1 antikoerper, PFP antikoerper, PRF1 antikoerper, Pfn antikoerper, Pfp antikoerper, Prf-1 antikoerper, Cyta antikoerper, RATCYTA antikoerper, LOC443187 antikoerper, perforin antikoerper, prf1 antikoerper, cytolysin antikoerper, perforin-1 antikoerper, perforin-1-like antikoerper, perforin 1 antikoerper, perforin 1 (pore forming protein) antikoerper, perforin antikoerper, perforin 1 L homeolog antikoerper, PRF1 antikoerper, Prf1 antikoerper, LOC443187 antikoerper, prf1 antikoerper, prf1.L antikoerper

Hintergrund:

Background: Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.

Aliases: Prf1 antibody, Pfp antibody, Perforin-1 antibody, P1 antibody, Cytolysin antibody, Lymphocyte pore-forming protein antibody

UniProt: P10820

Pathways: Apoptose, Caspase Kaskade in der Apoptose