GFER Antikörper (AA 1-198)

Produktnummer ABIN7178849

Produktdetails anti-GFER Antikörper

Target: GFER (Growth Factor, Augmenter of Liver Regeneration (GFER))

Bindungsspezifität: AA 1-198

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFER Antikörper ist unkonjugiert

Applikation: ELISA

Kreuzreaktivität: Ratte

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Rat FAD-linked sulfhydryl oxidase ALR protein (1-198AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu GFER

Target: GFER (Growth Factor, Augmenter of Liver Regeneration (GFER))

Andere Bezeichnung: Gfer (GFER Produkte)

Hintergrund:

Background: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen. May have a function in liver regeneration and spermatogenesis.

Aliases: Gfer antibody, AlrFAD-linked sulfhydryl oxidase ALR antibody, EC 1.8.3.2 antibody, Augmenter of liver regeneration antibody

UniProt: Q63042

Pathways: SARS-CoV-2 Protein Interaktom