Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Sortilin 1 Antikörper (AA 610-754) (Biotin)

SORT1 Reaktivität: Ratte ELISA Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN7179078
  • Target Alle Sortilin 1 (SORT1) Antikörper anzeigen
    Sortilin 1 (SORT1)
    Bindungsspezifität
    • 16
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 610-754
    Reaktivität
    • 45
    • 37
    • 32
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ratte
    Wirt
    • 46
    • 6
    • 2
    Kaninchen
    Klonalität
    • 49
    • 5
    Polyklonal
    Konjugat
    • 25
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Sortilin 1 Antikörper ist konjugiert mit Biotin
    Applikation
    • 38
    • 17
    • 17
    • 13
    • 13
    • 12
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA
    Kreuzreaktivität
    Ratte
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Rat Sortilin protein (610-754AA)
    Isotyp
    IgG
    Top Product
    Discover our top product SORT1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Sortilin 1 (SORT1)
    Andere Bezeichnung
    Sort1 (SORT1 Produkte)
    Synonyme
    SORT1 antikoerper, 19.m02079 antikoerper, gp95 antikoerper, ldlcq6 antikoerper, sortilin antikoerper, Gp95 antikoerper, LDLCQ6 antikoerper, NT3 antikoerper, 2900053A11Rik antikoerper, AI852375 antikoerper, Ntr3 antikoerper, Ntsr3 antikoerper, Nt3 antikoerper, Nts3 antikoerper, sort1 antikoerper, zgc:85953 antikoerper, sortilin 1 antikoerper, sortilin antikoerper, sortilin 1 S homeolog antikoerper, sortilin 1a antikoerper, SORT1 antikoerper, TP01_0016 antikoerper, BBOV_I002730 antikoerper, sort1.S antikoerper, Sort1 antikoerper, sort1a antikoerper
    Hintergrund

    Background: Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.

    Aliases: Sort1 antibody, Sortilin antibody, Glycoprotein 110 antibody, Gp110 antibody, Neurotensin receptor 3 antibody, NTR3 antibody

    UniProt
    O54861
    Pathways
    Neurotrophin Signalübertragung
Sie sind hier:
Kundenservice