SRI Antikörper (AA 32-116)

Produktnummer ABIN7179479

Produktdetails anti-SRI Antikörper

Target: SRI (Sorcin (SRI))

Bindungsspezifität: AA 32-116

Reaktivität: Staphylococcus aureus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRI Antikörper ist unkonjugiert

Applikation: ELISA

Kreuzreaktivität: Staphylococcus aureus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Staphylococcus aureus Staphylococcal complement inhibitor protein (32-116AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SRI

Target: SRI (Sorcin (SRI))

Andere Bezeichnung: scn (SRI Produkte)

Synonyme: zgc:64070 antikoerper, sri antikoerper, SRI antikoerper, CP-22 antikoerper, CP22 antikoerper, SCN antikoerper, V19 antikoerper, 2210417O06Rik antikoerper, 2900070H08Rik antikoerper, Sor antikoerper, sorcin antikoerper, Sorcin antikoerper, sorcin L homeolog antikoerper, sorcin S homeolog antikoerper, SRI antikoerper, sri antikoerper, EDI_060410 antikoerper, EDI_160670 antikoerper, EDI_002860 antikoerper, EDI_076560 antikoerper, CpipJ_CPIJ004933 antikoerper, CpipJ_CPIJ008581 antikoerper, Tsp_05707 antikoerper, sri.L antikoerper, sri.S antikoerper, Sri antikoerper

Hintergrund:

Background: Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation. The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium. Also prevents C5a-induced neutrophil responses.

Aliases: scn antibody, SA1754 antibody, Staphylococcal complement inhibitor antibody, SCIN antibody

UniProt: Q99SU9

Pathways: Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity