Streptococcal Pyrogenic Exotoxin B (SPEB) (AA 146-398) Antikörper

Produktnummer ABIN7179505

Produktdetails

Target: Streptococcal Pyrogenic Exotoxin B (SPEB)

Bindungsspezifität: AA 146-398

Reaktivität: Streptococcus pyogenes

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Kreuzreaktivität: Streptococcus pyogenes

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Streptococcus pyogenes serotype M28 Streptopain protein (146-398AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antigendetails

Target: Streptococcal Pyrogenic Exotoxin B (SPEB)

Andere Bezeichnung: speB (SPEB Produkte)

Synonyme: streptococcal pyrogenic exotoxin B antikoerper, speB antikoerper

Hintergrund:

Background: Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing (By similarity).

Aliases: speB antibody, M28_Spy1721 antibody, Streptopain antibody, EC 3.4.22.10 antibody, Exotoxin type B antibody, SPE B antibody, Streptococcal cysteine proteinase antibody, Streptococcus peptidase A antibody, SPP antibody

UniProt: Q48R29