Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.

eIF4EBP1 Antikörper (Thr70)

Name: eIF4EBP1 Antikörper (Thr70)
Brand: antibodies-online
SKU: ABIN7179966
Price: 392.04 EUR
Availability: InStock

EIF4EBP1 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of extracts from COS7 cells, treated with EGF (200 ng/mL, 30 mins), using 4E-BP1 (Ab-69) antibody. (eIF4EBP1 Antikörper (Thr70))

Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using 4E-BP1 (Ab-69) antibody. (eIF4EBP1 Antikörper (Thr70))

IHC

2 Abbildungen

Produktnummer ABIN7179966

Datenblatt (PDF)

Target Alle eIF4EBP1 (EIF4EBP1) Antikörper anzeigen

eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
Bindungsspezifität
28

20

20

19

16

15

10

10

7

7

7

6

6

5

4

4

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Thr70
Reaktivität
214

158

113

21

14

7

5

5

4

3

2

2

1

1

1
Human
Wirt
224

19

4
Kaninchen
Passende Sekundärantikörper
Klonalität
212

37
Polyklonal
Konjugat
103

22

17

11

8

6

6

6

6

6

6

6

6

5

5

5

5

5

3

3

3

3

3
Dieser eIF4EBP1 Antikörper ist unkonjugiert
Applikation
197

82

75

67

66

43

23

21

16

11

9

8

6

5

3

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Kreuzreaktivität

Human, Maus, Ratte

Aufreinigung

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

Synthesized non-phosphopeptide derived from Human 4E-BP1 around the phosphorylation site of threonine 70 (A-K-T-P-P).

Isotyp

IgG

Top Product

Discover our top product EIF4EBP1 Primärantikörper
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pThr37), (pThr46) antibody
EIF4EBP1 Reaktivität: Human, Maus WB, ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pSer65) antibody
EIF4EBP1 Reaktivität: Human IHC, ELISA, FACS, ICC Wirt: Maus Monoclonal 1E2E7 unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (C-Term) antibody
EIF4EBP1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pSer65) antibody
EIF4EBP1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 1-118) antibody
EIF4EBP1 Reaktivität: Human WB, ELISA, IF, PLA Wirt: Maus Monoclonal 4F3-H2 unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pThr36) antibody
EIF4EBP1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 2-111) antibody
EIF4EBP1 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 2-118) antibody
EIF4EBP1 Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 31-61) antibody
EIF4EBP1 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB11691 unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pThr45) antibody
EIF4EBP1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB:1:500-1:3000, IHC:1:50-1:100,

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C,-80 °C

Informationen zur Lagerung

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target

eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

Andere Bezeichnung

EIF4EBP1 (EIF4EBP1 Produkte)

Hintergrund

Background: Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.

Anne-Claude Gingras, Genes & Dev., Jun 1999, 13: 1422.
Guangming Liu, J. Biol. Chem., Mar 2002, 277: 8810 - 8816.
Ya-Ping Jiang, J. Biol. Chem., Mar 2001, 276: 10943 - 10951.
Anne-Claude Gingras, Genes & Dev., Feb 1998, 12: 502.
Aliases: 4E-BP1 antibody, 4EBP1 antibody, 4EBP1_HUMAN antibody, BP 1 antibody, eIF4E binding protein 1 antibody, eIF4E-binding protein 1 antibody, Eif4ebp1 antibody, Eukaryotic translation initiation factor 4E-binding protein 1 antibody, PHAS-I antibody, PHASI antibody, Phosphorylated heat- and acid-stable protein regulated by insulin 1 antibody

UniProt

Q13541

Pathways

MAPK Signalweg, PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, Regulation of Cell Size, BCR Signaling