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APLF Antikörper (Ser116)

APLF Reaktivität: Human ELISA, WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7179974
  • Target Alle APLF Antikörper anzeigen
    APLF (Aprataxin and PNKP Like Factor (APLF))
    Bindungsspezifität
    • 15
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Ser116
    Reaktivität
    • 34
    • 16
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 34
    Kaninchen
    Klonalität
    • 34
    Polyklonal
    Konjugat
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser APLF Antikörper ist unkonjugiert
    Applikation
    • 25
    • 13
    • 13
    • 12
    • 7
    • 4
    • 3
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogen
    Synthesized non-phosphopeptide derived from Human APLF around the phosphorylation site of serine 116 (R-N-S(p)-Q-V).
    Isotyp
    IgG
    Top Product
    Discover our top product APLF Primärantikörper
  • Applikationshinweise
    WB:1:500-1:3000, IHC:1:50-1:100,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    APLF (Aprataxin and PNKP Like Factor (APLF))
    Andere Bezeichnung
    APLF (APLF Produkte)
    Synonyme
    apfl antikoerper, palf antikoerper, xip1 antikoerper, APLF antikoerper, C2orf13 antikoerper, DKFZp459J1223 antikoerper, APFL antikoerper, PALF antikoerper, Xip1 antikoerper, 2010301N04Rik antikoerper, AI452191 antikoerper, RGD1565557 antikoerper, aprataxin and PNKP like factor antikoerper, APLF antikoerper, aplf antikoerper, Aplf antikoerper
    Hintergrund

    Background: Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage.

    Saunders W.S., J. Cell Sci. 104:573-582(1993).
    Ye Q., J. Biol. Chem. 271:14653-14656(1996).
    Ye Q., J. Biol. Chem. 272:14983-14989(1997).

    Aliases: 2010301N04Rik antibody, AI452191 antibody, Aplf antibody, APLF_HUMAN antibody, Aprataxin and PNK-like factor antibody, Apurinic-apyrimidinic endonuclease APLF antibody, C2orf13 antibody, PNK and APTX like FHA protein antibody, PNK and APTX-like FHA domain-containing protein antibody, RGD1565557 antibody, XIP1 antibody, XRCC1 interacting protein 1 antibody, XRCC1-interacting protein 1 antibody

    UniProt
    Q8IW19
    Pathways
    DNA Reparatur
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