Tryptophan Hydroxylase 2 Antikörper (Ser19)

Produktnummer ABIN7180101

Produktdetails anti-Tryptophan Hydroxylase 2 Antikörper

Target: Tryptophan Hydroxylase 2 (TPH2)

Bindungsspezifität: Ser19

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tryptophan Hydroxylase 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from Human TPH2 around the phosphorylation site of serine 19 (G-FI-S(p)-L-D).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Tryptophan Hydroxylase 2

Target: Tryptophan Hydroxylase 2 (TPH2)

Andere Bezeichnung: TPH2 (TPH2 Produkte)

Synonyme: ADHD7 antikoerper, NTPH antikoerper, Ntph antikoerper, tphR antikoerper, wu:fq15a04 antikoerper, AU043594 antikoerper, tryptophan hydroxylase 2 antikoerper, tryptophan hydroxylase 2 (tryptophan 5-monooxygenase) antikoerper, TPH2 antikoerper, Tph2 antikoerper, tph2 antikoerper

Hintergrund:

Background: This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.

Bader M., Science 299:76-76(2003).
Gibbs R.A., Nature 440:346-351(2006).
Pandey A., Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007).

Aliases: MGC138871 antibody, ADHD7 antibody, FLJ37295 antibody, MGC138872 antibody, Neuronal tryptophan hydroxylase antibody, NTPH antibody, TPH 2 antibody, Tph2 antibody, TPH2_HUMAN antibody, Tryptophan 5-hydroxylase 2 antibody, Tryptophan 5-monooxygenase 2 antibody, Tryptophan hydroxylase 2 antibody

UniProt: Q8IWU9