Pre-mRNA Branch Site Protein p14 (SF3B14) (C-Term) Antikörper

Produktnummer ABIN7180242

Produktdetails

Target: Pre-mRNA Branch Site Protein p14 (SF3B14)

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human SF3B14.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antigendetails

Target: Pre-mRNA Branch Site Protein p14 (SF3B14)

Andere Bezeichnung: SF3B6 (SF3B14 Produkte)

Synonyme: 6030419K15Rik antikoerper, AV001342 antikoerper, Sf3b14 antikoerper, zgc:86708 antikoerper, HSPC175 antikoerper, Ht006 antikoerper, P14 antikoerper, SAP14 antikoerper, SF3B14a antikoerper, splicing factor 3B, subunit 6 antikoerper, splicing factor 3b, subunit 6 antikoerper, splicing factor 3b subunit 6 S homeolog antikoerper, splicing factor 3b subunit 6 antikoerper, Sf3b6 antikoerper, sf3b6 antikoerper, sf3b6.S antikoerper, SF3B6 antikoerper

Hintergrund:

Background: Necessary for the splicing of pre-mRNA. Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing. Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively.

Will C.L., EMBO J. 20:4536-4546(2001).
Lai C.-H., Genome Res. 10:703-713(2000).
Zhang Q.-H., Genome Res. 10:1546-1560(2000).

Aliases: Ht006 antibody, P14 antibody, PM14_HUMAN antibody, Pre mRNA branch site protein p14 antibody, Pre-mRNA branch site protein p14 antibody, SAP14 antibody, SF3B 14 kDa subunit antibody, SF3B14 antibody, SF3B14a antibody, Splicing factor 3B, 14 kDa subunit antibody

UniProt: Q9Y3B4