UBA2 Antikörper (C-Term)

Produktnummer ABIN7180278

Produktdetails anti-UBA2 Antikörper

Target: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human Uba2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000, IHC:1:50-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu UBA2

Target: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Andere Bezeichnung: UBA2 (UBA2 Produkte)

Synonyme: ATSAE2 antikoerper, EMB2764 antikoerper, EMBRYO DEFECTIVE 2764 antikoerper, F3K23.23 antikoerper, F3K23_23 antikoerper, SUMO-ACTIVATING ENZYME 2 antikoerper, SUMO-activating enzyme 2 antikoerper, ARX antikoerper, SAE2 antikoerper, AA986091 antikoerper, Arx antikoerper, Sae2 antikoerper, UBA1 antikoerper, Ubl1a2 antikoerper, Uble1b antikoerper, sae2 antikoerper, sae2-B antikoerper, uba2-a antikoerper, uba2-b antikoerper, uble1b-B antikoerper, sae2b antikoerper, uble1b antikoerper, wu:fi17g06 antikoerper, zgc:66354 antikoerper, SUMO1 activating enzyme subunit 2 antikoerper, SUMO-activating enzyme 2 antikoerper, ubiquitin like modifier activating enzyme 2 antikoerper, ubiquitin-like modifier activating enzyme 2 antikoerper, ubiquitin like modifier activating enzyme 2 L homeolog antikoerper, MICPUN_63834 antikoerper, MICPUCDRAFT_36729 antikoerper, SAE2 antikoerper, UBA2 antikoerper, Uba2 antikoerper, uba2.L antikoerper, uba2 antikoerper

Hintergrund:

Background: The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

Mark H. L. Lambermon, Mol. Cell. Biol., Jun 2002, 22: 4346 - 4357.
Kyoung-Seok Ryu, J. Biol. Chem., Sep 2003, 278: 36621 - 36627.
R. Jrgen Dohmen, J. Biol. Chem., Jul 1995, 270: 18099.
Yoshiaki Azuma, FASEB J, Jun 2001, 10.1096.

Aliases: Anthracycline associated resistance ARX antibody, Anthracycline-associated resistance ARX antibody, ARX antibody, FLJ13058 antibody, HRIHFB2115 antibody, SAE 2 antibody, SAE2 antibody, SAE2_HUMAN antibody, SUMO 1 activating enzyme subunit 2 antibody, SUMO activating enzyme subunit 2 antibody, SUMO-activating enzyme subunit 2 antibody, UBA2 antibody, UBA2 ubiquitin activating enzyme E1 homolog antibody, Ubiquitin like 1 activating enzyme E1B antibody, Ubiquitin like modifier activating enzyme 2 antibody, Ubiquitin-like 1-activating enzyme E1B antibody, UBLE1B antibody

UniProt: Q9UBT2