beta Synuclein Antikörper
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- Target Alle beta Synuclein (SNCB) Antikörper anzeigen
- beta Synuclein (SNCB) (Synuclein, beta (SNCB))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser beta Synuclein Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from Human Synuclein beta antibody.
- Isotyp
- IgG
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- Applikationshinweise
- WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- beta Synuclein (SNCB) (Synuclein, beta (SNCB))
- Andere Bezeichnung
- SNCB (SNCB Produkte)
- Synonyme
- AI838531 antikoerper, betaSYN antikoerper, zgc:66343 antikoerper, sncb antikoerper, MGC75784 antikoerper, LOC619281 antikoerper, SNCB antikoerper, syub antikoerper, synuclein beta antikoerper, synuclein, beta antikoerper, synuclein beta L homeolog antikoerper, Beta-synuclein antikoerper, SNCB antikoerper, Sncb antikoerper, sncb antikoerper, sncb.L antikoerper, syub antikoerper
- Hintergrund
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Background: Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.
Yuxin Fan, Hum. Mol. Genet., Oct 2006, 15: 3002 - 3011.
Makoto Hashimoto, J. Biol. Chem., May 2004, 279: 23622 - 23629.
Cristine Alves da Costa, J. Biol. Chem., Sep 2003, 278: 37330 - 37335.
Heather Snyder, J. Biol. Chem., Mar 2005, 280: 7562 - 7569.Aliases: 14 kDa brain-specific protein antibody, Beta-synuclein antibody, Phosphoneuroprotein 14 antibody, PNP14 antibody, Sncb antibody, Synuclein beta antibody, SYUB_HUMAN antibody
- UniProt
- Q16143
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