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POLR3B Antikörper

POLR3B Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7184076
  • Target Alle POLR3B Antikörper anzeigen
    POLR3B (Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B))
    Reaktivität
    • 28
    • 27
    • 9
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 37
    • 2
    Kaninchen
    Klonalität
    • 37
    • 2
    Polyklonal
    Konjugat
    • 18
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser POLR3B Antikörper ist unkonjugiert
    Applikation
    • 27
    • 23
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogen
    Synthesized peptide derived from internal of Human RPC2.
    Isotyp
    IgG
    Top Product
    Discover our top product POLR3B Primärantikörper
  • Applikationshinweise
    WB:1:500-1:3000,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    POLR3B (Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B))
    Andere Bezeichnung
    POLR3B (POLR3B Produkte)
    Synonyme
    RGD1565311 antikoerper, C128 antikoerper, HLD8 antikoerper, RPC2 antikoerper, 2700078H01Rik antikoerper, A330032P03Rik antikoerper, C85372 antikoerper, RNA polymerase III subunit B antikoerper, polymerase (RNA) III (DNA directed) polypeptide B antikoerper, Polr3b antikoerper, POLR3B antikoerper
    Hintergrund

    Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft By similarity. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.

    Hu P., Mol. Cell. Biol. 22:8044-8055(2002).
    The MGC Project Team, Genome Res. 14:2121-2127(2004).
    Ota T., Nat. Genet. 36:40-45(2004).

    Aliases: C128 antibody, DNA directed RNA polymerase III 127.6 kDa polypeptide antibody, DNA directed RNA polymerase III subunit B antibody, DNA-directed RNA polymerase III 127.6 kDa polypeptide antibody, DNA-directed RNA polymerase III subunit B antibody, DNA-directed RNA polymerase III subunit RPC2 antibody, FLJ10388 antibody, polr3b antibody, Polymerase (RNA) III (DNA directed) polypeptide B antibody, RNA polymerase III subunit C2 antibody, RNA polymerase III subunit RPC2 antibody, RPC2 antibody, RPC2_HUMAN antibody

    UniProt
    Q9NW08
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