HCFC1 Antikörper (N-Term)

Produktnummer ABIN7184458

Produktdetails anti-HCFC1 Antikörper

Target: HCFC1 (Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HCFC1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from N-terminal of Human HCFC1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC:1:50-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HCFC1

Target: HCFC1 (Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1))

Andere Bezeichnung: HCFC1 (HCFC1 Produkte)

Synonyme: CFF antikoerper, HCF-1 antikoerper, HCF1 antikoerper, HFC1 antikoerper, MRX3 antikoerper, VCAF antikoerper, AW060991 antikoerper, HCF antikoerper, RGD1563804 antikoerper, fc61g09 antikoerper, hcfc1 antikoerper, im:7159458 antikoerper, wu:fc61g09 antikoerper, wu:fj40c12 antikoerper, HCFC1 antikoerper, host cell factor C1 antikoerper, host cell factor C1a antikoerper, host cell factor antikoerper, host cell factor C1 (VP16-accessory protein) antikoerper, HCFC1 antikoerper, Hcfc1 antikoerper, hcfc1a antikoerper, LOC5571204 antikoerper, CpipJ_CPIJ014908 antikoerper

Hintergrund:

Background: Involved in control of the cell cycle. Also antagonizes transactivation by ZBTB17 and GABP2, represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300. Coactivator for EGR2 and GABP2. Tethers the chromatin modifying Set1/Ash2 histone H3 'Lys-4' methyltransferase (H3K4me) and Sin3 histone deacetylase (HDAC) complexes (involved in the activation and repression of transcription, respectively) together. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. In case of human herpes simplex virus (HSV) infection, HCFC1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and POU2F1 thereby enabling the transcription of the viral immediate early genes.

Wilson A.C., Cell 74:115-125(1993).
Kristie T.M., J. Biol. Chem. 270:4387-4394(1995).
Ross M.T., Nature 434:325-337(2005).

Aliases: C1 factor antibody, CFF antibody, HCF 1 antibody, HCF antibody, HCF C-terminal chain 6 antibody, HCF-1 antibody, HCF1 antibody, Hcfc1 antibody, HCFC1_HUMAN antibody, HFC1 antibody, Host cell factor 1 antibody, Host cell factor antibody, Host cell factor C1 (VP16 accessory protein) antibody, Host cell factor C1 antibody, MGC70925 antibody, MRX3 antibody, VCAF antibody, VP16 accessory protein antibody

UniProt: P51610