KLHL3 Antikörper (N-Term)
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- Target Alle KLHL3 Antikörper anzeigen
- KLHL3 (Kelch-Like 3 (KLHL3))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KLHL3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from N-terminal of Human KLHL3.
- Isotyp
- IgG
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- Applikationshinweise
- WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- KLHL3 (Kelch-Like 3 (KLHL3))
- Andere Bezeichnung
- KLHL3 (KLHL3 Produkte)
- Synonyme
- 7530408C15Rik antikoerper, AI430941 antikoerper, EG627648 antikoerper, PHA2D antikoerper, RGD1565218 antikoerper, kelch like family member 3 antikoerper, kelch-like 3 antikoerper, kelch-like family member 3 antikoerper, KLHL3 antikoerper, Klhl3 antikoerper
- Hintergrund
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Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. The BCR(KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation.
Lai F., Genomics 66:65-75(2000).
Hirosawa M., DNA Res. 6:329-336(1999).
Ota T., Nat. Genet. 36:40-45(2004).Aliases: KLHL3 antibody, KIAA1129 antibody, Kelch-like protein 3 antibody
- UniProt
- Q9UH77
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