PDGFC Antikörper (AA 201-300)

Produktnummer ABIN714566

Produktdetails anti-PDGFC Antikörper

Target: PDGFC (Platelet-Derived Growth Factor C (PDGFC))

Bindungsspezifität: AA 201-300

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDGFC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDGFC/VEGF E

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-PDGFC Antikörper (ABIN714566)

Hurley, Adams, Wang, Jiang, Meo Burt, Du, Xiao: "Accelerated Fracture Healing in Transgenic Mice Overexpressing an Anabolic Isoform of Fibroblast Growth Factor 2." in: Journal of cellular biochemistry, (2015) (PubMed).

Details zu PDGFC

Target: PDGFC (Platelet-Derived Growth Factor C (PDGFC))

Andere Bezeichnung: PDGF C (PDGFC Produkte)

Synonyme: SCDGF antikoerper, FALLOTEIN antikoerper, 1110064L01Rik antikoerper, AI647969 antikoerper, PDGF-C antikoerper, platelet derived growth factor C antikoerper, platelet-derived growth factor, C polypeptide antikoerper, PDGFC antikoerper, Pdgfc antikoerper

Substanzklasse: Viral Protein

Hintergrund:

Synonyms: SCDGF, FALLOTEIN, Platelet-derived growth factor C, PDGF-C, Spinal cord-derived growth factor, VEGF-E, PDGFC, UNQ174/PRO2

Background: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen and chemoattractant for cells of mesenchymal origin. Required for normal skeleton formation during embryonic development, especially for normal development of the craniofacial skeleton and for normal development of the palate. Required for normal skin morphogenesis during embryonic development. Plays an important role in wound healing, where it appears to be involved in three stages: inflammation, proliferation and remodeling. Plays an important role in angiogenesis and blood vessel development. Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs. The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintenance of the latency of the PDGF domain. In the nucleus, PDGFC seems to have additional function.

Gen-ID: 56034

UniProt: Q9NRA1

Pathways: RTK Signalweg, Platelet-derived growth Factor Receptor Signaling