PDGFD Antikörper (AA 271-370)

Produktnummer ABIN714581

Produktdetails anti-PDGFD Antikörper

Target: PDGFD (Platelet Derived Growth Factor D (PDGFD))

Bindungsspezifität: AA 271-370

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDGFD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Sheep,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDGF-D

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-PDGFD Antikörper (ABIN714581)

Hurley, Adams, Wang, Jiang, Meo Burt, Du, Xiao: "Accelerated Fracture Healing in Transgenic Mice Overexpressing an Anabolic Isoform of Fibroblast Growth Factor 2." in: Journal of cellular biochemistry, (2015) (PubMed).

Details zu PDGFD

Target: PDGFD (Platelet Derived Growth Factor D (PDGFD))

Andere Bezeichnung: PDGF D (PDGFD Produkte)

Synonyme: IEGF antikoerper, SCDGF-B antikoerper, SCDGFB antikoerper, Scdgfb antikoerper, rSCDGF-B antikoerper, PDGFD antikoerper, 1110003I09Rik antikoerper, platelet derived growth factor D antikoerper, platelet-derived growth factor, D polypeptide antikoerper, PDGFD antikoerper, Pdgfd antikoerper

Hintergrund:

Synonyms: IEGF, SCDGFB, MSTP036, SCDGF-B, Platelet-derived growth factor D, PDGF-D, Iris-expressed growth factor, Spinal cord-derived growth factor B, PDGFD, UNQ1899/PRO4345

Background: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix (By similarity).

Gen-ID: 80310

UniProt: Q9GZP0

Pathways: RTK Signalweg, Platelet-derived growth Factor Receptor Signaling