ARHGAP24 Antikörper (AA 501-600)
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- Target Alle ARHGAP24 Antikörper anzeigen
- ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
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Bindungsspezifität
- AA 501-600
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ARHGAP24 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Homologie
- Human,Mouse,Rat
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ARHGAP24
- Isotyp
- IgG
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
- Andere Bezeichnung
- ARHGAP24 (ARHGAP24 Produkte)
- Synonyme
- FILGAP antikoerper, RC-GAP72 antikoerper, RCGAP72 antikoerper, p73 antikoerper, p73RhoGAP antikoerper, 0610025G21Rik antikoerper, si:ch211-65i12.2 antikoerper, Rho GTPase activating protein 24 antikoerper, ARHGAP24 antikoerper, Arhgap24 antikoerper, arhgap24 antikoerper
- Hintergrund
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Synonyms: Rho GTPase-activating protein 24, Filamin-A-associated RhoGAP, FilGAP, RAC1- and CDC42-specific GTPase-activating protein of 72 kDa, RC-GAP72, Rho-type GTPase-activating protein 24, RhoGAP of 73 kDa, Sarcoma antigen NY-SAR-88, p73RhoGAP, ARHGAP24, FILGAP
Background: Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.
- Gen-ID
- 83478
- UniProt
- Q8N264
- Pathways
- Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
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