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ARHGAP24 Antikörper (AA 501-600)

ARHGAP24 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN714716
  • Target Alle ARHGAP24 Antikörper anzeigen
    ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
    Bindungsspezifität
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    AA 501-600
    Reaktivität
    • 27
    • 10
    • 10
    • 1
    • 1
    Human
    Wirt
    • 25
    • 2
    Kaninchen
    Klonalität
    • 27
    Polyklonal
    Konjugat
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ARHGAP24 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 16
    • 3
    Western Blotting (WB), ELISA
    Homologie
    Human,Mouse,Rat
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ARHGAP24
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
    Andere Bezeichnung
    ARHGAP24 (ARHGAP24 Produkte)
    Synonyme
    FILGAP antikoerper, RC-GAP72 antikoerper, RCGAP72 antikoerper, p73 antikoerper, p73RhoGAP antikoerper, 0610025G21Rik antikoerper, si:ch211-65i12.2 antikoerper, Rho GTPase activating protein 24 antikoerper, ARHGAP24 antikoerper, Arhgap24 antikoerper, arhgap24 antikoerper
    Hintergrund

    Synonyms: Rho GTPase-activating protein 24, Filamin-A-associated RhoGAP, FilGAP, RAC1- and CDC42-specific GTPase-activating protein of 72 kDa, RC-GAP72, Rho-type GTPase-activating protein 24, RhoGAP of 73 kDa, Sarcoma antigen NY-SAR-88, p73RhoGAP, ARHGAP24, FILGAP

    Background: Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.

    Gen-ID
    83478
    UniProt
    Q8N264
    Pathways
    Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
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