ABCC5 Antikörper

Produktnummer ABIN7189591

Produktdetails anti-ABCC5 Antikörper

Target: ABCC5 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of Human ABCC5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ABCC5

Target: ABCC5 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5))

Andere Bezeichnung: ABCC5 (ABCC5 Produkte)

Synonyme: ABC33 antikoerper, EST277145 antikoerper, MOAT-C antikoerper, MOATC antikoerper, MRP5 antikoerper, SMRP antikoerper, pABC11 antikoerper, 2900011L11Rik antikoerper, AI132311 antikoerper, Abcc5a antikoerper, Abcc5b antikoerper, Mrp5 antikoerper, abc33 antikoerper, abcc5 antikoerper, moat-c antikoerper, moatc antikoerper, mrp5 antikoerper, pabc11 antikoerper, smrp antikoerper, ATP binding cassette subfamily C member 5 antikoerper, ATP-binding cassette, sub-family C (CFTR/MRP), member 5 antikoerper, ATP binding cassette subfamily C member 5 L homeolog antikoerper, ABCC5 antikoerper, Abcc5 antikoerper, abcc5.L antikoerper

Hintergrund:

Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing of this gene has been detected, however, the complete sequence and translation initiation site is unclear.

Aliases: ABC 33 antibody, ABC33 antibody, ABCC 5 antibody, Abcc5 antibody, ATP binding cassette sub family C (CFTR/MRP) member 5 antibody, ATP binding cassette sub family C member 5 antibody, ATP-binding cassette sub-family C member 5 antibody, Canalicular multispecific organic anion transporter C antibody, DKFZp686C1782 antibody, EST277145 antibody, MOAT C antibody, MOAT-C antibody, MOATC antibody, MRP 5 antibody, MRP5_HUMAN antibody, Multi specific organic anion tranporter C antibody, Multi-specific organic anion transporter C antibody, Multidrug resistance associated protein 5 antibody, Multidrug resistance-associated protein 5 antibody, pABC 11 antibody, pABC11 antibody, SMRP antibody

UniProt: O15440

Pathways: Glycosaminoglycan Metabolic Process