ANKRD28 Antikörper
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- Target Alle ANKRD28 Antikörper anzeigen
- ANKRD28 (Ankyrin Repeat Domain 28 (ANKRD28))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ANKRD28 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- Antigen affinity purification
- Immunogen
- Synthetic peptide of Human ANKRD28
- Isotyp
- IgG
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anti-Ankyrin Repeat Domain 28 (ANKRD28) (AA 430-530) antibody
ANKRD28 Reaktivität: Ratte WB, IF (p), IF (cc), ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Ankyrin Repeat Domain 28 (ANKRD28) (AA 1-300) antibodyANKRD28 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- ELISA:1:1000-1:2000, WB:1:200-1:1000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- ANKRD28 (Ankyrin Repeat Domain 28 (ANKRD28))
- Andere Bezeichnung
- ANKRD28 (ANKRD28 Produkte)
- Hintergrund
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Background: Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation. ANKRD28 selectively regulated phosphorylation of hnRNP-K at ser284, an effect that was enhanced in vivo by an S1013A/S1017A double mutant, suggesting that ANKRD28 targets PP1 in a regulated manner to dephosphorylate hnRNP-K selectively at ser284.
Aliases: ANKRD28 antibody, KIAA0379Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A antibody, PP6-ARS-A antibody, Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A antibody, Ankyrin repeat domain-containing protein 28 antibody, Phosphatase interactor targeting protein hnRNP K antibody, PITK antibody
- UniProt
- O15084
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