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DLC1 Antikörper (AA 1-80) (Biotin)

DLC1 Reaktivität: Human ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN714958
  • Target Alle DLC1 Antikörper anzeigen
    DLC1 (Deleted in Liver Cancer 1 (DLC1))
    Bindungsspezifität
    • 14
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-80
    Reaktivität
    • 38
    • 11
    • 10
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 36
    • 3
    • 1
    Kaninchen
    Klonalität
    • 39
    • 1
    Polyklonal
    Konjugat
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DLC1 Antikörper ist konjugiert mit Biotin
    Applikation
    • 13
    • 13
    • 11
    • 10
    • 8
    • 8
    • 5
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Cow,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human DLC1
    Isotyp
    IgG
    Top Product
    Discover our top product DLC1 Primärantikörper
  • Applikationshinweise
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    DLC1 (Deleted in Liver Cancer 1 (DLC1))
    Andere Bezeichnung
    DLC1 (DLC1 Produkte)
    Synonyme
    ARHGAP7 antikoerper, HP antikoerper, STARD12 antikoerper, p122-RhoGAP antikoerper, rhogap7 antikoerper, DLC-1 antikoerper, StARD12 antikoerper, Dlc-1 antikoerper, A730069N07Rik antikoerper, Arhgap7 antikoerper, dlc-1 antikoerper, RhoGAP antikoerper, Dlc1 antikoerper, DLC1 Rho GTPase activating protein antikoerper, DLC1 Rho GTPase activating protein S homeolog antikoerper, rho GTPase-activating protein 7 antikoerper, deleted in liver cancer 1 antikoerper, DLC1 antikoerper, dlc1.S antikoerper, dlc1 antikoerper, LOC100456847 antikoerper, Dlc1 antikoerper, LOC100729904 antikoerper
    Hintergrund

    Synonyms: LC8, PIN, DLC1, DLC8, LC8a, DNCL1, hdlc1, DNCLC1, Dynein light chain 1, cytoplasmic, 8 kDa dynein light chain, Dynein light chain LC8-type 1, Protein inhibitor of neuronal nitric oxide synthase, DYNLL1

    Background: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Binds and inhibits the catalytic activity of neuronal nitric oxide synthase. Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1. Regulates apoptotic activities of BCL2L11 by sequestering it to microtubules. Upon apoptotic stimuli the BCL2L11-DYNLL1 complex dissociates from cytoplasmic dynein and translocates to mitochondria and sequesters BCL2 thus neutralizing its antiapoptotic activity.

    Gen-ID
    8655
    UniProt
    P63167
    Pathways
    Tube Formation, Positive Regulation of Endopeptidase Activity
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