Caspase 2 Antikörper (AA 251-350) (Cy7)
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- Target Alle Caspase 2 (CASP2) Antikörper anzeigen
- Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
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Bindungsspezifität
- AA 251-350
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Caspase 2 Antikörper ist konjugiert mit Cy7
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Applikation
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Kreuzreaktivität
- Human
- Homologie
- Mouse,Rat,Cow,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Caspase 2
- Isotyp
- IgG
- Top Product
- Discover our top product CASP2 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
- Andere Bezeichnung
- Caspase 2 (CASP2 Produkte)
- Synonyme
- xCaspase-2 antikoerper, Caspase-2 antikoerper, ICH-1 antikoerper, Nedd2 antikoerper, CASP-2 antikoerper, ICH1 antikoerper, NEDD-2 antikoerper, NEDD2 antikoerper, PPP1R57 antikoerper, ICH-1L/1S antikoerper, ICH1L1S antikoerper, caspase 2 antikoerper, caspase 2 L homeolog antikoerper, caspase-2 antikoerper, CASP2 antikoerper, casp2.L antikoerper, CpipJ_CPIJ008254 antikoerper, Casp2 antikoerper
- Hintergrund
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Synonyms: Apoptosis related cysteine peptidase, CASP 2, Casp 2L Pro, CASP2, Caspase 2 apoptosis related cysteine protease, Caspase2, Developmentally down regulated 2, ICH 1, ICH 1 protease, ICH 1L, ICH 1L/1S, ICH1, ICH1 protease, ICH1L, ICH1L/1S, NEDD 2, NEDD2, NEDD2 apoptosis regulatory gene, Neural precursor cell expressed, Neural precursor cell expressed developmentally down regulated 2.
Background: Caspase 2 has a positive and a negative role in the regulation of the apoptotic process. Overexpression of the full length Caspase 2 (Nedd2/Ich1) mRNA in some cell types results in apoptosis, whereas overexpression of an alternative Caspase 2 splice variant suppresses apoptosis induced by serum withdrawal. Caspase 2 may be activated in vitro by Caspase 1, Caspase 3 and the neutral serine protease granzyme B which is stored in the specialized lytic granules of cytotoxic lymphocytes.
- Gen-ID
- 835
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose, Neurotrophin Signalübertragung
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