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SPAG1 Antikörper

SPAG1 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7192612
  • Target Alle SPAG1 Antikörper anzeigen
    SPAG1 (Sperm Associated Antigen 1 (SPAG1))
    Reaktivität
    • 29
    • 1
    • 1
    • 1
    Human
    Wirt
    • 28
    • 1
    Kaninchen
    Klonalität
    • 29
    Polyklonal
    Konjugat
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SPAG1 Antikörper ist unkonjugiert
    Applikation
    • 22
    • 15
    • 15
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    Antigen affinity purification
    Immunogen
    Synthetic peptide of Human SPAG1
    Isotyp
    IgG
    Top Product
    Discover our top product SPAG1 Primärantikörper
  • Applikationshinweise
    ELISA:1:1000-1:5000, IHC:1:25-1:100,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SPAG1 (Sperm Associated Antigen 1 (SPAG1))
    Andere Bezeichnung
    SPAG1 (SPAG1 Produkte)
    Synonyme
    cb1089 antikoerper, MGC162178 antikoerper, wu:fj78g10 antikoerper, sp75 antikoerper, tpis antikoerper, hsd-3.8 antikoerper, HSD-3.8 antikoerper, SP75 antikoerper, TPIS antikoerper, sperm associated antigen 1 antikoerper, sperm associated antigen 1a antikoerper, SPAG1 antikoerper, spag1a antikoerper, CpipJ_CPIJ006297 antikoerper, spag1 antikoerper, Spag1 antikoerper
    Hintergrund

    Background: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein.

    Aliases: SPAG1 antibody, Sperm-associated antigen 1 antibody, HSD-3.8 antibody, Infertility-related sperm protein Spag-1 antibody

    UniProt
    Q07617
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