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CD46 Antikörper (AA 35-179)

CD46 Reaktivität: Human FACS, ELISA, IHC Wirt: Maus Monoclonal 1A5A5 unconjugated
Produktnummer ABIN7193208
  • Target Alle CD46 Antikörper anzeigen
    CD46
    Bindungsspezifität
    • 16
    • 14
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 35-179
    Reaktivität
    • 118
    • 34
    • 20
    • 10
    • 10
    • 1
    Human
    Wirt
    • 83
    • 51
    • 2
    Maus
    Klonalität
    • 73
    • 63
    Monoklonal
    Konjugat
    • 49
    • 16
    • 15
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD46 Antikörper ist unkonjugiert
    Applikation
    • 84
    • 77
    • 41
    • 37
    • 30
    • 16
    • 14
    • 14
    • 12
    • 9
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC)
    Verwendungszweck
    CD46 Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human CD46 (AA: 35-179) expressed in E. Coli.
    Klon
    1A5A5
    Isotyp
    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    CD46
    Andere Bezeichnung
    CD46 (CD46 Produkte)
    Synonyme
    AHUS2 antikoerper, MCP antikoerper, MIC10 antikoerper, TLX antikoerper, TRA2.10 antikoerper, Mcp antikoerper, CD46 antikoerper, CD46 molecule antikoerper, CD46 antigen, complement regulatory protein antikoerper, CD46 molecule, complement regulatory protein antikoerper, membrane cofactor protein-like antikoerper, CD46 antikoerper, Cd46 antikoerper, LOC100341359 antikoerper, LOC103789310 antikoerper
    Hintergrund

    Description:

    The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

    Aliases: MCP, TLX, AHUS2, MIC10, TRA2.10

    Molekulargewicht
    43.7kDa
    Gen-ID
    4179
    UniProt
    P15529
    Pathways
    Regulation of Actin Filament Polymerization
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