CD46 Antikörper (AA 35-179)
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- Target Alle CD46 Antikörper anzeigen
- CD46
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Bindungsspezifität
- AA 35-179
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD46 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC)
- Verwendungszweck
- CD46 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human CD46 (AA: 35-179) expressed in E. Coli.
- Klon
- 1A5A5
- Isotyp
- IgG1
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- CD46
- Andere Bezeichnung
- CD46 (CD46 Produkte)
- Synonyme
- AHUS2 antikoerper, MCP antikoerper, MIC10 antikoerper, TLX antikoerper, TRA2.10 antikoerper, Mcp antikoerper, CD46 antikoerper, CD46 molecule antikoerper, CD46 antigen, complement regulatory protein antikoerper, CD46 molecule, complement regulatory protein antikoerper, membrane cofactor protein-like antikoerper, CD46 antikoerper, Cd46 antikoerper, LOC100341359 antikoerper, LOC103789310 antikoerper
- Hintergrund
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Description:
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
Aliases: MCP, TLX, AHUS2, MIC10, TRA2.10
- Molekulargewicht
- 43.7kDa
- Gen-ID
- 4179
- UniProt
- P15529
- Pathways
- Regulation of Actin Filament Polymerization
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