PLAUR Antikörper (AA 23-305)
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- Target Alle PLAUR Antikörper anzeigen
- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
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Bindungsspezifität
- AA 23-305
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PLAUR Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human CD87 (AA: 23-305) expressed in E. coli.
- Klon
- 1D1B11
- Isotyp
- IgG2b
- Top Product
- Discover our top product PLAUR Primärantikörper
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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- Target
- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
- Andere Bezeichnung
- CD87 (PLAUR Produkte)
- Synonyme
- Cd87 antikoerper, u-PAR antikoerper, uPAR antikoerper, CD87 antikoerper, U-PAR antikoerper, UPAR antikoerper, URKR antikoerper, Par antikoerper, Plaur3 antikoerper, uPAR-2 antikoerper, uPAR-3 antikoerper, PLAUR antikoerper, plasminogen activator, urokinase receptor antikoerper, Plaur antikoerper, PLAUR antikoerper
- Hintergrund
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Description: This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
Aliases: PLAUR, UPAR, URKR, U-PAR
- Molekulargewicht
- 37 kDa
- Gen-ID
- 5329
- Pathways
- Inositol Metabolic Process
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