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IL21 Receptor Antikörper (AA 20-232)

IL21R Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 8H10G4D12 unconjugated
Produktnummer ABIN7193230
  • Target Alle IL21 Receptor (IL21R) Antikörper anzeigen
    IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
    Bindungsspezifität
    • 15
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-232
    Reaktivität
    • 35
    • 34
    • 7
    • 2
    Human
    Wirt
    • 42
    • 7
    • 7
    • 3
    Maus
    Klonalität
    • 44
    • 14
    • 1
    Monoklonal
    Konjugat
    • 30
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL21 Receptor Antikörper ist unkonjugiert
    Applikation
    • 36
    • 20
    • 13
    • 13
    • 11
    • 10
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    Verwendungszweck
    CD360 Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human CD360 (AA: 20-232) expressed in E. Coli.
    Klon
    8H10G4D12
    Isotyp
    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
    Andere Bezeichnung
    CD360 (IL21R Produkte)
    Synonyme
    IL21R antikoerper, il-21ra.a antikoerper, CD360 antikoerper, NILR antikoerper, interleukin 21 receptor antikoerper, interleukin 21 receptor, tandem duplicate 1 antikoerper, IL21R antikoerper, il21r.1 antikoerper, Il21r antikoerper
    Hintergrund

    Description:

    The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.

    Aliases: IL21R, NILR, IMD56

    Molekulargewicht
    59.1kDa
    Gen-ID
    50615
    UniProt
    Q9HBE5
    Pathways
    JAK-STAT Signalweg
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