LRP6 Antikörper (AA 1198-1370)
-
- Target Alle LRP6 Antikörper anzeigen
- LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
-
Bindungsspezifität
- AA 1198-1370
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser LRP6 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human LRP6 (AA: extra 1198-1370) expressed in E. coli.
- Klon
- 1A3F5
- Isotyp
- IgG1
-
-
- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
-
- Target
- LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
- Andere Bezeichnung
- LRP6 (LRP6 Produkte)
- Synonyme
- lrp6-A antikoerper, Xlrp6 antikoerper, adcad2 antikoerper, lrp6 antikoerper, LRP6 antikoerper, ADCAD2 antikoerper, C030016K15Rik antikoerper, Cd antikoerper, Gw antikoerper, LDL receptor related protein 6 antikoerper, LDL receptor related protein 6 L homeolog antikoerper, LDL receptor related protein 6 S homeolog antikoerper, low density lipoprotein receptor-related protein 6 antikoerper, low-density lipoprotein receptor-related protein 6 antikoerper, LRP6 antikoerper, lrp6.L antikoerper, lrp6.S antikoerper, lrp6 antikoerper, Lrp6 antikoerper, LOC590395 antikoerper
- Hintergrund
-
Description: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
Aliases: ADCAD2, STHAG7
- Molekulargewicht
- 180 kDa
- Gen-ID
- 4040
- Pathways
- WNT Signalweg, Tube Formation
-