CD43 Antikörper (AA 20-253)
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- Target Alle CD43 (SPN) Antikörper anzeigen
- CD43 (SPN) (Sialophorin (SPN))
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Bindungsspezifität
- AA 20-253
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD43 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), ELISA
- Verwendungszweck
- CD43 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human CD43 (AA: 20-253) expressed in E. Coli.
- Klon
- 1H8B10
- Isotyp
- IgG1
- Top Product
- Discover our top product SPN Primärantikörper
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- CD43 (SPN) (Sialophorin (SPN))
- Andere Bezeichnung
- CD43 (SPN Produkte)
- Synonyme
- CD43 antikoerper, GALGP antikoerper, GPL115 antikoerper, LSN antikoerper, A630014B01Rik antikoerper, Cd43 antikoerper, Galgp antikoerper, Ly-48 antikoerper, Ly48 antikoerper, Lsn antikoerper, Lsn1 antikoerper, gpL115 antikoerper, sialophorin antikoerper, SPN antikoerper, Spn antikoerper
- Hintergrund
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Description:
This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome.
Aliases: SPN, LSN, GALGP, GPL115
- Molekulargewicht
- 40.3kDa
- Gen-ID
- 6693
- UniProt
- P16150
- Pathways
- Regulation of Leukocyte Mediated Immunity
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