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CD43 Antikörper (AA 20-253)

SPN Reaktivität: Human FACS, ELISA Wirt: Maus Monoclonal 1H8B10 unconjugated
Produktnummer ABIN7193295
  • Target Alle CD43 (SPN) Antikörper anzeigen
    CD43 (SPN) (Sialophorin (SPN))
    Bindungsspezifität
    • 17
    • 13
    • 12
    • 12
    • 10
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-253
    Reaktivität
    • 150
    • 33
    • 8
    Human
    Wirt
    • 95
    • 64
    • 27
    Maus
    Klonalität
    • 101
    • 84
    • 1
    Monoklonal
    Konjugat
    • 65
    • 21
    • 19
    • 19
    • 14
    • 10
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD43 Antikörper ist unkonjugiert
    Applikation
    • 103
    • 96
    • 61
    • 61
    • 42
    • 18
    • 18
    • 13
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), ELISA
    Verwendungszweck
    CD43 Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human CD43 (AA: 20-253) expressed in E. Coli.
    Klon
    1H8B10
    Isotyp
    IgG1
    Top Product
    Discover our top product SPN Primärantikörper
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    CD43 (SPN) (Sialophorin (SPN))
    Andere Bezeichnung
    CD43 (SPN Produkte)
    Synonyme
    CD43 antikoerper, GALGP antikoerper, GPL115 antikoerper, LSN antikoerper, A630014B01Rik antikoerper, Cd43 antikoerper, Galgp antikoerper, Ly-48 antikoerper, Ly48 antikoerper, Lsn antikoerper, Lsn1 antikoerper, gpL115 antikoerper, sialophorin antikoerper, SPN antikoerper, Spn antikoerper
    Hintergrund

    Description:

    This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome.

    Aliases: SPN, LSN, GALGP, GPL115

    Molekulargewicht
    40.3kDa
    Gen-ID
    6693
    UniProt
    P16150
    Pathways
    Regulation of Leukocyte Mediated Immunity
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