SIGLEC5 Antikörper (AA 17-230)

Produktnummer ABIN7193301

Produktdetails anti-SIGLEC5 Antikörper

Target: SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))

Bindungsspezifität: AA 17-230

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SIGLEC5 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Verwendungszweck: CD170 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CD170 (AA: 17-230) expressed in E. Coli.

Klon: 3F5A3

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu SIGLEC5

Target: SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))

Andere Bezeichnung: CD170 (SIGLEC5 Produkte)

Synonyme: CD170 antikoerper, CD33L2 antikoerper, OB-BP2 antikoerper, OBBP2 antikoerper, SIGLEC-5 antikoerper, sialic acid binding Ig like lectin 5 antikoerper, sialic acid-binding Ig-like lectin 5 antikoerper, sialic acid binding Ig-like lectin 5 antikoerper, SIGLEC5 antikoerper, LOC100597560 antikoerper, Siglec5 antikoerper

Hintergrund:

Description:

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.

Aliases: SIGLEC5, OBBP2, CD33L2, OB-BP2, SIGLEC-5

Molekulargewicht: 60.7kDa

Gen-ID: 8778

UniProt: O15389