IDH2 Antikörper (AA 1-143)
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- Target Alle IDH2 Antikörper anzeigen
- IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
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Bindungsspezifität
- AA 1-143
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser IDH2 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Verwendungszweck
- IDH2 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human IDH2 (AA: 1-143) expressed in E. Coli.
- Klon
- 3E8E9
- Isotyp
- IgG1
- Top Product
- Discover our top product IDH2 Primärantikörper
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
- Andere Bezeichnung
- IDH2 (IDH2 Produkte)
- Hintergrund
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Description:
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Aliases: IDH, IDP, IDHM, IDPM, ICD-M, D2HGA2, mNADP-IDH
- Molekulargewicht
- 50.9kDa
- Gen-ID
- 3418
- UniProt
- P48735
- Pathways
- Warburg Effekt
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