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IDH2 Antikörper (AA 1-143)

IDH2 Reaktivität: Human ELISA, IHC, FACS Wirt: Maus Monoclonal 3E8E9 unconjugated
Produktnummer ABIN7193379
  • Target Alle IDH2 Antikörper anzeigen
    IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
    Bindungsspezifität
    • 16
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-143
    Reaktivität
    • 65
    • 52
    • 42
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 58
    • 6
    • 1
    Maus
    Klonalität
    • 51
    • 14
    Monoklonal
    Konjugat
    • 31
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IDH2 Antikörper ist unkonjugiert
    Applikation
    • 45
    • 18
    • 15
    • 13
    • 13
    • 12
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Verwendungszweck
    IDH2 Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human IDH2 (AA: 1-143) expressed in E. Coli.
    Klon
    3E8E9
    Isotyp
    IgG1
    Top Product
    Discover our top product IDH2 Primärantikörper
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
    Andere Bezeichnung
    IDH2 (IDH2 Produkte)
    Hintergrund

    Description:

    Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

    Aliases: IDH, IDP, IDHM, IDPM, ICD-M, D2HGA2, mNADP-IDH

    Molekulargewicht
    50.9kDa
    Gen-ID
    3418
    UniProt
    P48735
    Pathways
    Warburg Effekt
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