PIDD Antikörper (AA 776-910)
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- Target Alle PIDD Antikörper anzeigen
- PIDD (P53-Induced Death Domain Protein (PIDD))
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Bindungsspezifität
- AA 776-910
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PIDD Antikörper ist unkonjugiert
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Applikation
- ELISA
- Verwendungszweck
- PIDD1 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human PIDD1 (AA: 776-910) expressed in E. Coli.
- Klon
- 3C5G8
- Isotyp
- IgG1
- Top Product
- Discover our top product PIDD Primärantikörper
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- Applikationshinweise
- ELISA: 1/10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- PIDD (P53-Induced Death Domain Protein (PIDD))
- Andere Bezeichnung
- PIDD1 (PIDD Produkte)
- Synonyme
- 1200011D09Rik antikoerper, AU042446 antikoerper, Pidd antikoerper, LRDD antikoerper, Lrdd antikoerper, p53 induced death domain protein 1 antikoerper, p53-induced death domain protein 1 antikoerper, Pidd1 antikoerper, PIDD1 antikoerper
- Hintergrund
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Description:
The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]
Aliases: LRDD, PIDD
- Molekulargewicht
- 99.7kDa
- Gen-ID
- 55367
- UniProt
- Q9HB75
- Pathways
- p53 Signalweg, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
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