LILRB1 Antikörper (AA 338-461)
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- Target Alle LILRB1 Antikörper anzeigen
- LILRB1 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1))
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Bindungsspezifität
- AA 338-461
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser LILRB1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human LILRB1 (AA: extra 338-461) expressed in E. coli.
- Klon
- 4B5A4
- Isotyp
- IgG1
- Top Product
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- Applikationshinweise
- WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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- Target
- LILRB1 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1))
- Andere Bezeichnung
- LILRB1 (LILRB1 Produkte)
- Synonyme
- CD85J antikoerper, ILT-2 antikoerper, ILT2 antikoerper, LIR-1 antikoerper, LIR1 antikoerper, MIR-7 antikoerper, MIR7 antikoerper, leukocyte immunoglobulin like receptor B1 antikoerper, LILRB1 antikoerper
- Hintergrund
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Description: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Aliases: ILT2, LIR1, MIR7, PIRB, CD85J, ILT-2, LIR-1, MIR-7, PIR-B
- Molekulargewicht
- 70.8 kDa
- Gen-ID
- 10859
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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