KDM2A Antikörper (AA 1-150)
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- Target Alle KDM2A Antikörper anzeigen
- KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))
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Bindungsspezifität
- AA 1-150
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser KDM2A Antikörper ist unkonjugiert
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Applikation
- ELISA
- Verwendungszweck
- KDM2A Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human KDM2A (AA: 1-150) expressed in E. Coli.
- Klon
- 5C11F7
- Isotyp
- IgG1
- Top Product
- Discover our top product KDM2A Primärantikörper
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- Applikationshinweise
- ELISA: 1/10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))
- Andere Bezeichnung
- KDM2A (KDM2A Produkte)
- Hintergrund
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Description:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Aliases: FBL7, CXXC8, FBL11, FBXL11, JHDM1A, LILINA
- Molekulargewicht
- 132.8kDa
- Gen-ID
- 22992
- UniProt
- Q9Y2K7
- Pathways
- Warburg Effekt
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