ATR Antikörper (AA 366-550)
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- Target Alle ATR Antikörper anzeigen
- ATR (ATR serine/threonine kinase (ATR))
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Bindungsspezifität
- AA 366-550
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ATR Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB), Flow Cytometry (FACS)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human ATR (AA: 366-550) expressed in E. coli.
- Klon
- 3G6D2
- Isotyp
- IgG1
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- Applikationshinweise
- WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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- Target
- ATR (ATR serine/threonine kinase (ATR))
- Andere Bezeichnung
- ATR (ATR Produkte)
- Synonyme
- FCTCS antikoerper, FRP1 antikoerper, MEC1 antikoerper, SCKL antikoerper, SCKL1 antikoerper, ATR serine/threonine kinase antikoerper, ataxia telangiectasia and Rad3 related antikoerper, ATR antikoerper, Atr antikoerper
- Hintergrund
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Description: The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.
Aliases: FRP1, MEC1, SCKL, FCTCS, SCKL1
- Molekulargewicht
- 301 kDa
- Gen-ID
- 545
- Pathways
- Positive Regulation of Response to DNA Damage Stimulus
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