GANP Antikörper (AA 293-442)

Produktnummer ABIN7193448

Produktdetails anti-GANP Antikörper

Target: GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))

Bindungsspezifität: AA 293-442

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GANP Antikörper ist unkonjugiert

Applikation: ELISA

Verwendungszweck: MCM3AP Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human MCM3AP (AA: 293-442) expressed in E. Coli.

Klon: 5B2C4

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu GANP

Target: GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))

Andere Bezeichnung: MCM3AP (MCM3AP Produkte)

Hintergrund:

Description:

The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability.

Aliases: GANP, SAC3, MAP80, PNRIID

Molekulargewicht: 218.4kDa

Gen-ID: 8888

UniProt: O60318

Pathways: Protein targeting to Nucleus