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Mesothelin Antikörper (AA 37-286)

MSLN Reaktivität: Human ELISA, WB, FACS Wirt: Maus Monoclonal 5C11A4 unconjugated
Produktnummer ABIN7193453
  • Target Alle Mesothelin (MSLN) Antikörper anzeigen
    Mesothelin (MSLN)
    Bindungsspezifität
    • 16
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 37-286
    Reaktivität
    • 92
    • 18
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 76
    • 23
    • 4
    • 1
    • 1
    Maus
    Klonalität
    • 75
    • 28
    • 2
    Monoklonal
    Konjugat
    • 65
    • 10
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Mesothelin Antikörper ist unkonjugiert
    Applikation
    • 66
    • 47
    • 23
    • 22
    • 12
    • 10
    • 9
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Flow Cytometry (FACS)
    Verwendungszweck
    MSLN Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human MSLN (AA: 37-286) expressed in E. Coli.
    Klon
    5C11A4
    Isotyp
    IgG2b
    Top Product
    Discover our top product MSLN Primärantikörper
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    Mesothelin (MSLN)
    Andere Bezeichnung
    MSLN (MSLN Produkte)
    Synonyme
    MPF antikoerper, SMRP antikoerper, MSLN antikoerper, mesothelin antikoerper, MSLN antikoerper, Msln antikoerper, LOC611363 antikoerper, LOC100524016 antikoerper
    Hintergrund

    Description:

    This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

    Aliases: MPF, SMRP

    Molekulargewicht
    69kDa
    Gen-ID
    10232
    UniProt
    Q13421
    Pathways
    EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
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