ULBP1 Antikörper (AA 26-216)

Produktnummer ABIN7193457

Produktdetails anti-ULBP1 Antikörper

Target: ULBP1 (UL16 Binding Protein 1 (ULBP1))

Bindungsspezifität: AA 26-216

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ULBP1 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Verwendungszweck: ULBP1 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human ULBP1 (AA: 26-216) expressed in E. Coli.

Klon: 3A6F11

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu ULBP1

Target: ULBP1 (UL16 Binding Protein 1 (ULBP1))

Andere Bezeichnung: ULBP1 (ULBP1 Produkte)

Synonyme: RAET1I antikoerper, A430108B07Rik antikoerper, MULT1 antikoerper, ULBP1 antikoerper, UL16 binding protein 1 antikoerper, UL16 binding protein 21 antikoerper, NKG2D ligand 1 antikoerper, ULBP1 antikoerper, ULBP21 antikoerper, Ulbp1 antikoerper, LOC100683099 antikoerper

Hintergrund:

Description:

The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

Aliases: N2DL-1, RAET1I, NKG2DL1

Molekulargewicht: 28kDa

Gen-ID: 80329

UniProt: Q9BZM6

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process