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Caspase 9 Antikörper (AA 331-416)

CASP9 Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 5E8C8 unconjugated
Produktnummer ABIN7193461
  • Target Alle Caspase 9 (CASP9) Antikörper anzeigen
    Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
    Bindungsspezifität
    • 28
    • 16
    • 16
    • 16
    • 16
    • 9
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 331-416
    Reaktivität
    • 218
    • 132
    • 108
    • 19
    • 17
    • 16
    • 10
    • 1
    • 1
    • 1
    Human
    Wirt
    • 213
    • 15
    Maus
    Klonalität
    • 205
    • 23
    Monoklonal
    Konjugat
    • 117
    • 10
    • 9
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    Dieser Caspase 9 Antikörper ist unkonjugiert
    Applikation
    • 199
    • 81
    • 67
    • 67
    • 60
    • 48
    • 40
    • 39
    • 18
    • 17
    • 16
    • 5
    • 3
    • 3
    • 1
    ELISA, Flow Cytometry (FACS)
    Verwendungszweck
    CASP9 Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human CASP9 (AA: 331-416) expressed in E. Coli.
    Klon
    5E8C8
    Isotyp
    IgG1
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    Discover our top product CASP9 Primärantikörper
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
    Andere Bezeichnung
    CASP9 (CASP9 Produkte)
    Synonyme
    CASP9 antikoerper, AI115399 antikoerper, APAF-3 antikoerper, AW493809 antikoerper, CASP-9 antikoerper, Caspase-9 antikoerper, ICE-LAP6 antikoerper, Mch6 antikoerper, Apaf3 antikoerper, Casp-9-CTD antikoerper, Casp9_v1 antikoerper, Ice-Lap6 antikoerper, APAF3 antikoerper, MCH6 antikoerper, PPP1R56 antikoerper, caspase 9 antikoerper, CASP9 antikoerper, Casp9 antikoerper
    Hintergrund

    Description:

    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1, this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

    Aliases: MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6

    Molekulargewicht
    46.3kDa
    Gen-ID
    842
    UniProt
    P55211
    Pathways
    MAPK Signalweg, RTK Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Endopeptidase Activity
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