NOXA Antikörper (AA 1-54)
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- Target Alle NOXA (PMAIP1) Antikörper anzeigen
- NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
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Bindungsspezifität
- AA 1-54
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser NOXA Antikörper ist unkonjugiert
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Applikation
- ELISA, Flow Cytometry (FACS)
- Verwendungszweck
- PMAIP1 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human PMAIP1 (AA: 1-54) expressed in E. Coli.
- Klon
- 1A2D3
- Isotyp
- IgG1
- Top Product
- Discover our top product PMAIP1 Primärantikörper
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anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (AA 1-54) antibody
PMAIP1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (AA 1-136) antibodyPMAIP1 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) antibodyPMAIP1 Reaktivität: Human WB, IHC Wirt: Maus Monoclonal 114C307-1 unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (AA 1-136) antibodyPMAIP1 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (Internal Region) antibodyVerified PMAIP1 Reaktivität: Human WB, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (N-Term) antibodyPMAIP1 Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
- Andere Bezeichnung
- PMAIP1 (PMAIP1 Produkte)
- Synonyme
- TN3 antikoerper, PMAIP1 antikoerper, zgc:162379 antikoerper, APR antikoerper, NOXA antikoerper, Noxa antikoerper, phorbol-12-myristate-13-acetate-induced protein 1 antikoerper, PMAIP1 antikoerper, pmaip1 antikoerper, Pmaip1 antikoerper
- Hintergrund
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Description:
The protein encoded by this gene promotes activation of caspases and apoptosis, Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
Aliases: APR, NOXA
- Molekulargewicht
- 6kDa
- Gen-ID
- 5366
- UniProt
- Q13794
- Pathways
- p53 Signalweg, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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