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CD8 alpha Antikörper (AA 22-235)

CD8A Reaktivität: Human FACS, WB, ELISA Wirt: Maus Monoclonal 8H8A8 unconjugated
Produktnummer ABIN7193490
  • Target Alle CD8 alpha (CD8A) Antikörper anzeigen
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Bindungsspezifität
    • 16
    • 15
    • 10
    • 9
    • 9
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-235
    Reaktivität
    • 205
    • 117
    • 47
    • 45
    • 15
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 173
    • 127
    • 104
    Maus
    Klonalität
    • 297
    • 103
    • 1
    Monoklonal
    Konjugat
    • 118
    • 46
    • 36
    • 30
    • 30
    • 11
    • 9
    • 8
    • 8
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD8 alpha Antikörper ist unkonjugiert
    Applikation
    • 310
    • 129
    • 92
    • 67
    • 65
    • 46
    • 22
    • 19
    • 15
    • 14
    • 14
    • 11
    • 10
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), ELISA
    Verwendungszweck
    CD8a Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human CD8a (AA: 22-235) expressed in E. Coli.
    Klon
    8H8A8
    Isotyp
    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Andere Bezeichnung
    CD8a (CD8A Produkte)
    Synonyme
    cd8 antikoerper, LOC100136450 antikoerper, BB154331 antikoerper, Ly-2 antikoerper, Ly-35 antikoerper, Ly-B antikoerper, Lyt-2 antikoerper, zgc:136643 antikoerper, CD8 antikoerper, Leu2 antikoerper, MAL antikoerper, p32 antikoerper, RHACD8-4 antikoerper, CD8a molecule antikoerper, uncharacterized LOC100125537 antikoerper, CD8 alpha antikoerper, CD8 antigen, alpha chain antikoerper, T-cell surface glycoprotein CD8 alpha chain antikoerper, Cd8a antikoerper, LOC100125537 antikoerper, LOC100136450 antikoerper, CD8A antikoerper, cd8a antikoerper, LOC100126556 antikoerper
    Hintergrund

    Description:

    The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.

    Aliases: CD8, p32, Leu2

    Molekulargewicht
    25.7kDa
    Gen-ID
    925
    UniProt
    P01732
    Pathways
    T-Zell Rezeptor Signalweg
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