FGF2 Antikörper (AA 143-288)

Produktnummer ABIN7193503

Produktdetails anti-FGF2 Antikörper

Target: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Bindungsspezifität: AA 143-288

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FGF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human FGF2 (AA: 143-288) expressed in E. coli.

Klon: 1D6B5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB:1:500 - 1:2000, ICC:1:200 - 1:1000, ELISA:1:10000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu FGF2

Target: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Andere Bezeichnung: FGF2 (FGF2 Produkte)

Synonyme: BFGF antikoerper, FGF-2 antikoerper, FGFB antikoerper, HBGF-2 antikoerper, Fgf-2 antikoerper, Fgfb antikoerper, bFGF antikoerper, fibroblast growth factor 2 antikoerper, fibroblast growth factor 2 (basic) antikoerper, FGF2 antikoerper, Fgf2 antikoerper, fgf2 antikoerper

Hintergrund:

Description: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

Aliases: BFGF, FGFB, FGF-2, HBGF-2

Molekulargewicht: 30.7 kDa

Gen-ID: 2247

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteine