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MSH6 Antikörper (AA 217-395)

MSH6 Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 1D1C2 unconjugated
Produktnummer ABIN7193511
  • Target Alle MSH6 Antikörper anzeigen
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    Bindungsspezifität
    • 15
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 217-395
    Reaktivität
    • 75
    • 35
    • 27
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 56
    • 16
    • 3
    Maus
    Klonalität
    • 44
    • 31
    Monoklonal
    Konjugat
    • 43
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MSH6 Antikörper ist unkonjugiert
    Applikation
    • 51
    • 25
    • 23
    • 18
    • 14
    • 13
    • 11
    • 8
    • 8
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Verwendungszweck
    MSH6 Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human MSH6 (AA: 217-395) expressed in E. Coli.
    Klon
    1D1C2
    Isotyp
    IgG1
    Top Product
    Discover our top product MSH6 Primärantikörper
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    Andere Bezeichnung
    MSH6 (MSH6 Produkte)
    Synonyme
    GTBP antikoerper, GTMBP antikoerper, HNPCC5 antikoerper, HSAP antikoerper, p160 antikoerper, cb326 antikoerper, wu:fb36c12 antikoerper, LOC100227810 antikoerper, AU044881 antikoerper, AW550279 antikoerper, Gtmbp antikoerper, mutS homolog 6 antikoerper, mutS homolog 6 (E. coli) antikoerper, DNA mismatch repair protein antikoerper, MSH6 antikoerper, msh6 antikoerper, Msh6 antikoerper
    Hintergrund

    Description:

    This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.

    Aliases: GTBP, HSAP, p160, GTMBP, HNPCC5

    Molekulargewicht
    152.8kDa
    Gen-ID
    2956
    UniProt
    P52701
    Pathways
    DNA Reparatur, Chromatin Binding, Production of Molecular Mediator of Immune Response
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