Mesothelin Antikörper (AA 296-606)
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- Target Alle Mesothelin (MSLN) Antikörper anzeigen
- Mesothelin (MSLN)
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Bindungsspezifität
- AA 296-606
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Mesothelin Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB)
- Verwendungszweck
- MSLN Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human MSLN (AA: 296-606) expressed in E. Coli.
- Klon
- 7E6A6
- Isotyp
- IgG1
- Top Product
- Discover our top product MSLN Primärantikörper
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- Applikationshinweise
- ELISA: 1/10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- Mesothelin (MSLN)
- Andere Bezeichnung
- MSLN (MSLN Produkte)
- Synonyme
- MPF antikoerper, SMRP antikoerper, MSLN antikoerper, mesothelin antikoerper, MSLN antikoerper, Msln antikoerper, LOC611363 antikoerper, LOC100524016 antikoerper
- Hintergrund
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Description:
This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Aliases: MPF, SMRP
- Molekulargewicht
- 69kDa
- Gen-ID
- 10232
- UniProt
- Q13421
- Pathways
- EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
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