Asialoglycoprotein Receptor 2 Antikörper (AA 80-311)

Produktnummer ABIN7193549

Produktdetails anti-Asialoglycoprotein Receptor 2 Antikörper

Target: Asialoglycoprotein Receptor 2 (ASGR2)

Bindungsspezifität: AA 80-311

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Asialoglycoprotein Receptor 2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Verwendungszweck: ASGR2 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human ASGR2 (AA: 80-311) expressed in E. Coli.

Klon: 2C6D11

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu Asialoglycoprotein Receptor 2

Target: Asialoglycoprotein Receptor 2 (ASGR2)

Andere Bezeichnung: ASGR2 (ASGR2 Produkte)

Synonyme: ASGR2 antikoerper, asgr2 antikoerper, MGC137129 antikoerper, ASGP-R2 antikoerper, ASGPR2 antikoerper, CLEC4H2 antikoerper, HBXBP antikoerper, HL-2 antikoerper, Asgr antikoerper, Asgr-2 antikoerper, asialoglycoprotein receptor 2 antikoerper, C-type lectin domain family 10 member A antikoerper, ASGR2 antikoerper, clec10a antikoerper, Asgr2 antikoerper, LOC100347178 antikoerper

Hintergrund:

Description:

This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Aliases: HL-2, HBXBP, ASGPR2, ASGP-R2, CLEC4H2

Molekulargewicht: 35kDa

Gen-ID: 433

UniProt: P07307

Pathways: Thyroid Hormone Synthesis