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IL4 Receptor Antikörper (AA 26-232)

IL4R Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 4B12B12 unconjugated
Produktnummer ABIN7193555
  • Target Alle IL4 Receptor (IL4R) Antikörper anzeigen
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    Bindungsspezifität
    • 16
    • 15
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 26-232
    Reaktivität
    • 65
    • 50
    • 22
    Human
    Wirt
    • 77
    • 11
    • 8
    • 2
    • 1
    Maus
    Klonalität
    • 82
    • 16
    • 1
    Monoklonal
    Konjugat
    • 50
    • 9
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL4 Receptor Antikörper ist unkonjugiert
    Applikation
    • 80
    • 31
    • 27
    • 14
    • 14
    • 13
    • 11
    • 9
    • 7
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human CD124 (AA: 26-232) expressed in E. coli.
    Klon
    4B12B12
    Isotyp
    IgG1
    Top Product
    Discover our top product IL4R Primärantikörper
  • Applikationshinweise
    WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Target
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    Andere Bezeichnung
    CD124 (IL4R Produkte)
    Synonyme
    IL4R antikoerper, il-4ra antikoerper, zgc:113063 antikoerper, CD124 antikoerper, IL-4RA antikoerper, IL4RA antikoerper, Il4ra antikoerper, IL4 antikoerper, Il4r antikoerper, interleukin 4 receptor antikoerper, interleukin 4 receptor, tandem duplicate 1 antikoerper, interleukin 4 receptor, alpha antikoerper, IL4R antikoerper, il4r.1 antikoerper, Il4r antikoerper, Il4ra antikoerper
    Hintergrund

    Description: This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.

    Aliases: IL4R, IL4RA, IL-4RA

    Molekulargewicht
    89.7 kDa
    Gen-ID
    3566
    Pathways
    JAK-STAT Signalweg, Positive Regulation of Immune Effector Process
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