TIA1 Antikörper (AA 1-215)
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- Target Alle TIA1 Antikörper anzeigen
- TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))
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Bindungsspezifität
- AA 1-215
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser TIA1 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Verwendungszweck
- TIA1 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human TIA1 (AA: 1-215) expressed in E. Coli.
- Klon
- 3A3B9
- Isotyp
- IgG1
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200-1/400
ICC: 1/200 - 1/1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))
- Andere Bezeichnung
- TIA1 (TIA1 Produkte)
- Hintergrund
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Description:
The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15- kDa protein that is thought to be derived from the carboxyl terminus of the 40- kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for this gene.
Aliases: WDM, TIA-1
- Molekulargewicht
- 43kDa
- Gen-ID
- 7072
- UniProt
- P31483
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