SAA1 Antikörper (AA 19-212)

Produktnummer ABIN7193595

Produktdetails anti-SAA1 Antikörper

Target: SAA1 (Serum Amyloid A1 (SAA1))

Bindungsspezifität: AA 19-212

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SAA1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Verwendungszweck: SAA1 Antibody

Sequenz: SFFSFLGEAF DGARDMWRAY SDMREANYIG SDKYFHARGN YDAAKRGPGG AWAAEVITDA RENIQRFFGH GAEDSLADQA ANEWGRSGKD PNHFRPAGLP EKY

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human SAA1 (AA: 19-212) expressed in E. Coli.

Klon: 1A12E5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200-1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu SAA1

Target: SAA1 (Serum Amyloid A1 (SAA1))

Andere Bezeichnung: SAA1 (SAA1 Produkte)

Hintergrund:

Description:

This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11. [provided by RefSeq, Feb 2016]

Aliases: SAA, PIG4, SAA2, TP53I4

Molekulargewicht: 13.5kDa

Gen-ID: 6288

UniProt: P0DJI8

Pathways: Toll-Like Receptors Cascades