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MYLK Antikörper (AA 1375-1524)

MYLK Reaktivität: Human WB, ELISA, IHC, ICC, FACS Wirt: Maus Monoclonal 7F2B11 unconjugated
Produktnummer ABIN7193606
  • Target Alle MYLK Antikörper anzeigen
    MYLK (Myosin Light Chain Kinase (MYLK))
    Bindungsspezifität
    • 15
    • 8
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1375-1524
    Reaktivität
    • 78
    • 41
    • 36
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 87
    • 3
    • 3
    • 1
    Maus
    Klonalität
    • 82
    • 12
    Monoklonal
    Konjugat
    • 41
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MYLK Antikörper ist unkonjugiert
    Applikation
    • 38
    • 35
    • 24
    • 13
    • 13
    • 11
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Verwendungszweck
    MYLK Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human MYLK (AA:1375-1524) expressed in E. Coli.
    Klon
    7F2B11
    Isotyp
    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200-1/400

    ICC: 1/200 - 1/1000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    MYLK (Myosin Light Chain Kinase (MYLK))
    Andere Bezeichnung
    MYLK (MYLK Produkte)
    Synonyme
    AAT7 antikoerper, KRP antikoerper, MLCK antikoerper, MLCK1 antikoerper, MLCK108 antikoerper, MLCK210 antikoerper, MSTP083 antikoerper, MYLK1 antikoerper, smMLCK antikoerper, 9530072E15Rik antikoerper, A930019C19Rik antikoerper, AW489456 antikoerper, Mlck antikoerper, SMMLCK antikoerper, mlck antikoerper, fj60a06 antikoerper, mlck1a antikoerper, mylk antikoerper, wu:fj60a06 antikoerper, zmlck1 antikoerper, myosin light chain kinase antikoerper, myosin, light polypeptide kinase antikoerper, myosin, light chain kinase a antikoerper, MYLK antikoerper, Mylk antikoerper, mylka antikoerper
    Hintergrund

    Description:

    This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts.

    Aliases: KRP, AAT7, MLCK, MLCK1, MMIHS, MYLK1, s mMLCK, MLCK108, MLCK210, MSTP083

    Molekulargewicht
    210kDa
    Gen-ID
    4638
    UniProt
    Q15746
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