Prosaposin Antikörper (AA 17-216)
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- Target Alle Prosaposin (PSAP) Antikörper anzeigen
- Prosaposin (PSAP)
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Bindungsspezifität
- AA 17-216
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Prosaposin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Verwendungszweck
- PSAP Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human PSAP (AA: 17-216) expressed in E. Coli.
- Klon
- 3B4A8
- Isotyp
- IgG1
- Top Product
- Discover our top product PSAP Primärantikörper
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200-1/400
ICC: 1/200 - 1/1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- Prosaposin (PSAP)
- Andere Bezeichnung
- PSAP (PSAP Produkte)
- Hintergrund
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Description:
This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Aliases: GLBA, SAP1, SAP2
- Molekulargewicht
- 58.1kDa
- Gen-ID
- 5660
- UniProt
- P07602
- Pathways
- Positive Regulation of Endopeptidase Activity
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